This article was originally published by The Wellcome Trust on 28th June 2017 and can be accessed here.
Researchers at the Wellcome Trust Sanger Institute have zoomed in on a a list of genes that trigger Inflammatory Bowel Disease (IBD):
“Scientists at Sanger examined the genome of 67,852 people. They then used three statistical methods to zoom in on variations in the genome which are actively implicated in the disease. Of the regions of the genome associated with IBD they studied, 18 could be pin-pointed to a single genetic variant.”
If successful, we could see increased effectiveness of existing drugs and the development of new ones:
“This new research has produced a high-resolution map of the disease. It allows scientists to separate the genetic variants into those that directly influence IBD and those that just happen to be located near each other in the genome.”